Lymphocyte blastogenesis in the diagnosis of tuberculosis in cattle

Conference · Fri Dec 31 23:00:00 EST 1976

OSTI ID:7106919

Thoen, C O; Muscoplat, C C; Cram, L S; Jarnagin, J L; Johnson, D C; Pietz, D E

Considerable progress has been made towards the eradication of tuberculosis in cattle in the United States. No reliable blood test has been developed for detecting infected animals. An in vitro test for tuberculosis must have a high level of sensitivity with adequate specificity to differentiate infections due to Mycobacterium bovis and those caused by other mycobacteria. Moreover, it would be desirable that the test system be simple ad readily automated. The accuracy of lymphocyte immunostimulation tests which are considered to be in vitro correlates of delayed-type tuberculin skin hypersensitivity is discussed.

• Research Organization: Los Alamos Scientific Lab., NM (USA)
• DOE Contract Number: W-7405-ENG-36
• OSTI ID: 7106919
• Report Number(s): LA-UR-77-95; CONF-770125-2
• Country of Publication: United States
• Language: English

Related Subjects

550900 -- Pathology
553000* -- Agriculture & Food Technology
59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
ANIMAL CELLS
ANIMALS
BACTERIA
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CATTLE
CELL FLOW SYSTEMS
CONNECTIVE TISSUE CELLS
DIAGNOSTIC TECHNIQUES
DISEASES
DNA
DOMESTIC ANIMALS
DYES
IMMUNE REACTIONS
IN VITRO
INFECTIOUS DISEASES
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MEDICINE
MICROORGANISMS
MYCOBACTERIUM
MYCOBACTERIUM TUBERCULOSIS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
RUMINANTS
SOMATIC CELLS
TUBERCULOSIS
VERTEBRATES
VETERINARY MEDICINE