Synthesis of thiazolidines of the indole series based on 2-chloro-1-(3-indolyl)ethanone and its derivatives

Journal Article · Thu Nov 19 23:00:00 EST 1987 · J. Org. Chem. USSR (Engl. Transl.); (United States)

OSTI ID:7076581

Povalyaeva, O S; Kurkovskaya, L N; Vigdorchik, M M; Suvorov, N N

The reactions of 2-chloro-1-(3-indolyl)ethanone and its derivatives with homoveratrylamine, cysteamine, and cystamine were investigated. The amino group is alkylated in the case of homoveratrylamine, and the mercapto group in the case of cysteamine. A nontrivial path was found in the reaction of 3-chloro-acetylindoles with cystamine, as a result of which thiazolidines were obtained.

• Research Organization: D. I. Mendeleev Moscow Chemical Technology Institute (USSR)
• OSTI ID: 7076581
• Journal Information: J. Org. Chem. USSR (Engl. Transl.); (United States), Journal Name: J. Org. Chem. USSR (Engl. Transl.); (United States) Vol. 23:6; ISSN JOCYA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
640302 -- Atomic
Molecular & Chemical Physics-- Atomic & Molecular Properties & Theory
74 ATOMIC AND MOLECULAR PHYSICS
ALKYLATION
AMINES
AROMATICS
AZAARENES
AZOLES
CHEMICAL REACTION KINETICS
CHEMICAL REACTIONS
CHEMICAL SHIFT
CHLORINATED ALIPHATIC HYDROCARBONS
CHLOROFORM
COUPLING
COUPLING CONSTANTS
DEUTERIUM COMPOUNDS
HALOGENATED ALIPHATIC HYDROCARBONS
HETEROCYCLIC COMPOUNDS
HYDROGEN COMPOUNDS
HYDROGEN TRANSFER
HYPERFINE STRUCTURE
INDOLES
INFRARED SPECTRA
INTERMEDIATE COUPLING
ISOMERIZATION
ISOTOPE EFFECTS
J-J COUPLING
KETONES
KINETICS
MASS SPECTRA
NMR SPECTRA
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PYRROLES
REACTION KINETICS
SPECTRA
SYNTHESIS
THIAZOLES