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Stereochemistry of the Diels-Alder reaction of butadiene with cyclopropene

Journal Article · · Journal of Organic Chemistry; (USA)
DOI:https://doi.org/10.1021/jo00283a018· OSTI ID:7071639
1(E)-Deuteriobutadiene and cyclopropene react at 0{degree}C to give 2-endo-deuteriobicyclo(4.1.0)hept-3-ene; 1-(Z)-deuteriobutadiene leads to the 2-exo-deuterio bicyclic product. Analysis of these products through {sup 2}H NMR spectroscopy reveals complete stereospecificity, indicating that the transition structure having an endo orientation of diene and cyclopropene is strongly favored over the alternative exo geometry.
OSTI ID:
7071639
Journal Information:
Journal of Organic Chemistry; (USA), Journal Name: Journal of Organic Chemistry; (USA) Vol. 54:22; ISSN JOCEA; ISSN 0022-3263
Country of Publication:
United States
Language:
English