Revascularization of autogenous skin grafts placed on irradiated tissue
Journal Article
·
· J Oral Maxillofac Surg; (United States)
Vascular changes in rat skin after irradiation were examined microangiographically. Revascularization of the skin transplanted during the chronic stage after irradiation was also studied. The results obtained through these examinations revealed higher vascular densities at the acute and the subacute stages, and low values at the chronic stages compared with those of the control. Furthermore, when the skin grafts were transplanted to the irradiated beds in the chronic stage, primary revascularization was scant, and the inhibited capillary proliferation in the recipient sites prevented new vessel penetration. This explains why grafts transplanted to previously irradiated beds fail to survive.
- Research Organization:
- Department of Oral Surgery, School of Medicine, Nagoya University, Nagoya, Japan
- OSTI ID:
- 7069412
- Journal Information:
- J Oral Maxillofac Surg; (United States), Journal Name: J Oral Maxillofac Surg; (United States) Vol. 40:8
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560152 -- Radiation Effects on Animals-- Animals
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
BODY
CAPILLARIES
CARDIOVASCULAR SYSTEM
CELL PROLIFERATION
DIAGNOSTIC TECHNIQUES
DOSES
GRAFTS
GROWTH
IRRADIATION
LOCAL IRRADIATION
MAMMALS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIATION DOSES
RADIATION EFFECTS
RADIOLOGY
RATS
RODENTS
SIDE EFFECTS
SKIN
TRANSPLANTS
VERTEBRATES
560152 -- Radiation Effects on Animals-- Animals
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
BODY
CAPILLARIES
CARDIOVASCULAR SYSTEM
CELL PROLIFERATION
DIAGNOSTIC TECHNIQUES
DOSES
GRAFTS
GROWTH
IRRADIATION
LOCAL IRRADIATION
MAMMALS
MEDICINE
NUCLEAR MEDICINE
ORGANS
RADIATION DOSES
RADIATION EFFECTS
RADIOLOGY
RATS
RODENTS
SIDE EFFECTS
SKIN
TRANSPLANTS
VERTEBRATES