Metallothionein: A potential biomonitor of exposure to environmental toxins
Conference
·
· Preprints of Papers Presented at National Meeting, Division of Water, Air and Waste Chemistry, American Chemical Society; (USA)
OSTI ID:7067391
- Syracuse Univ., NY (USA)
The metal-binding protein, metallothionein (MT), is a potential biomonitor for assessment of exposure of feral animals to environmental toxins. The protein is ubiquitous and is induced not only by zinc and copper but by numerous metals and by stresses which may be associated with environmental pollution. The RIA developed for detection and quantitation of MT has demonstrated its utility in performing this function on all mammalian isoforms studied to date; the ELISA has proved to be a similarly useful complement to the RIA in this regard. Antibodies specific for a particular non-mammalian isoform of interest may be developed to provide the same capability for monitoring possible toxic states in invertebrates and microorganisms.
- OSTI ID:
- 7067391
- Report Number(s):
- CONF-8909236--
- Conference Information:
- Journal Name: Preprints of Papers Presented at National Meeting, Division of Water, Air and Waste Chemistry, American Chemical Society; (USA) Journal Volume: 28:2
- Country of Publication:
- United States
- Language:
- English
Similar Records
Metallothionein is a reliable indicator of metal exposure in fish
Effects of cadmium and environmental pollution on metallothionein and cytochrome P450 in Tilapia
Expression of mammalian metallothionein genes in Escherichia coli and in Saccharomyces cerevisiae
Conference
·
Sat Dec 30 23:00:00 EST 1995
·
OSTI ID:392323
Effects of cadmium and environmental pollution on metallothionein and cytochrome P450 in Tilapia
Journal Article
·
Mon Jul 01 00:00:00 EDT 1996
· Bulletin of Environmental Contamination and Toxicology
·
OSTI ID:456759
Expression of mammalian metallothionein genes in Escherichia coli and in Saccharomyces cerevisiae
Technical Report
·
Fri Aug 01 00:00:00 EDT 1986
·
OSTI ID:6943151
Related Subjects
54 ENVIRONMENTAL SCIENCES
540120 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (1990-)
540220 -- Environment
Terrestrial-- Chemicals Monitoring & Transport-- (1990-)
550501 -- Metabolism-- Tracer Techniques
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOASSAY
BIOLOGICAL INDICATORS
BIOLOGICAL STRESS
BIOSYNTHESIS
COPPER
DIAGNOSTIC TECHNIQUES
ELEMENTS
ENVIRONMENTAL EXPOSURE
ENZYME IMMUNOASSAY
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
METABOLISM
METALLOPROTEINS
METALLOTHIONEIN
METALS
ORGANIC COMPOUNDS
POLLUTION
PROTEINS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNODETECTION
RADIOIMMUNOLOGY
SYNTHESIS
TRACER TECHNIQUES
TRANSITION ELEMENTS
WILD ANIMALS
ZINC
540120 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (1990-)
540220 -- Environment
Terrestrial-- Chemicals Monitoring & Transport-- (1990-)
550501 -- Metabolism-- Tracer Techniques
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOASSAY
BIOLOGICAL INDICATORS
BIOLOGICAL STRESS
BIOSYNTHESIS
COPPER
DIAGNOSTIC TECHNIQUES
ELEMENTS
ENVIRONMENTAL EXPOSURE
ENZYME IMMUNOASSAY
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
METABOLISM
METALLOPROTEINS
METALLOTHIONEIN
METALS
ORGANIC COMPOUNDS
POLLUTION
PROTEINS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNODETECTION
RADIOIMMUNOLOGY
SYNTHESIS
TRACER TECHNIQUES
TRANSITION ELEMENTS
WILD ANIMALS
ZINC