Sequential thallium-201 myocardial scintigraphy after acute infarction in man

Journal Article · Tue Jul 01 04:00:00 EDT 1980 · Radiology; (United States)

OSTI ID:7065253

Fletcher, J W; Mueller, H S; Rao, P S

Three sequential Tl-201 myocardial perfusion studies were performed in 21 patients (18 men, 3 women) with first acute transmural myocardia infarction. The Tl-201 image defect size was determined with a semiquantitative visual scoring method and temporal changes in image defect size were compared to CK-MB infarct size and enzymatic evidence of progressive myocardial necrosis and infarct extension. Progressive decreases in Tl-201 image defect size were observed and the visual score in all 21 patients decreased significantly from 6.5 +- 3.7 (mean +- SD) on day 1 to 4.9 +- 3.5 on day 12. Eleven patients without evidence of infarct extension had significantly lower infarct size, a significant decrease in visual score by the 12th day and had significantly smaller Tl-201 defects at all three study times compared to 10 patients with infarct extension. Seven of 10 (70%) with extension had an initial visual score greater than or equal to 7 compared to only 2/11 (18%) without extension. The temporal behavior of Tl-201 image defects is related to the size of the infarction and presence or absence of extension. Sequential studies comparing early initial and subsequent defect size may assist in evaluating the behavior of ischemic and infarcted myocardium in the postinfarction period.

• Research Organization: St. Louis Univ., MO
• OSTI ID: 7065253
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 136:1; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550900 -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENZYME ACTIVITY
HEART
HEAVY NUCLEI
IMAGE PROCESSING
ISCHEMIA
ISOTOPES
MINUTES LIVING RADIOISOTOPES
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NECROSIS
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
PROCESSING
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIONUCLIDE KINETICS
SCINTISCANNING
THALLIUM 210
THALLIUM ISOTOPES
VASCULAR DISEASES