Acute myocardial infarction imaged with /sup 99m/Tc-stannous pyrophosphate and /sup 201/Tl: a clinical evaluation

Journal Article · Wed Sep 01 00:00:00 EDT 1976 · J. Nucl. Med.; (United States)

OSTI ID:7337463

Parkey, R W; Bonte, F J; Stokely, E M; Lewis, S E; Graham, K D; Buja, L M; Willerson, J T

Twenty-six patients suspected of having acute myocardial infarction (AMI) underwent myocardial scintigraphy sequentially with /sup 201/Tl and /sup 99m/Tc-stannous pyrophosphate (/sup 99m/Tc-PP/sub i/). Of the 26 patients, 24 had AMI documented by enzyme and electrocardiographic changes. Nineteen had transmural and five had subendocardial myocardial infarctions. The remaining two patients had ''unstable angina pectoris.'' The mean time from onset to imaging was 4 days. Of the 24 patients with AMI, 22 had positive /sup 99m/Tc-PP/sub i/ scintigrams. In 20 the area of acute myocardial damage appeared to be the same by /sup 99m/Tc-PP/sub i/ scintigram as by ECG; in two, the location could not be precisely determined. The two patients with negative /sup 99m/Tc-PP/sub i/ scintigrams at the time of combined myocardial imaging had had positive /sup 99m/Tc-PP/sub i/ images previously. In all 24 patients, the /sup 201/Tl images were abnormal in at least the location suggested by the electrocardiogram. In seven patients, the area of decreased /sup 201/Tl activity was grossly equal to the positive area on the /sup 99m/Tc-PP/sub i/ images; in 15, the /sup 201/Tl defect was definitely larger; and in two, the /sup 201/Tl defect appeared slightly smaller. Although the /sup 99m/Tc-PP/sub i/ and /sup 201/Tl myocardial images provide different information, both are valuable in determining the overall integrity of the myocardium in patients with ischemic heart disease.

• Research Organization: Univ. of Texas Health Science Center, Dallas
• OSTI ID: 7337463
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 17:9; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
HEART
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MYOCARDIAL INFARCTION
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PATIENTS
PHOSPHORUS COMPOUNDS
PYROPHOSPHATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
TECHNETIUM 99
TECHNETIUM ISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
YEARS LIVING RADIOISOTOPES