Effect on days of lactation and methionine hydroxy analog on incorporation of plasma fatty acids into plasma triglycerides

Journal Article · Sun Jan 01 04:00:00 EST 1989 · Journal of Dairy Science; (USA)

DOI:https://doi.org/10.3168/jds.S0022-0302(89)79079-2· OSTI ID:7059786

Pullen, D L; Emergy, R S ^[1]; Palmquist, D L ^[2]

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1. Michigan State Univ., East Lancing (USA)
2. Ohio State Univ., Wooster (USA)

Methionine hydroxy analog has been proposed to stimulate hepatic lipoprotein synthesis and incorporation of plasma fatty acids into plasma triglyceride. Seven cows were fed diets containing 0 to 30 g analog/d starting 14 d prepartum. At approximately 30 and 60 d postpartum, cows were continuously infused intravenously with 1-({sup 14}C)palmitic acid for 160 min to achieve steady-state labeling of plasma fatty acid and triglyceride. Turnover of fatty acid and transfer quotients for triglyceride and CO{sub 2} were 3.3 an 2.7 mmol min{sup {minus}1}; 13.0 and 10.0%; and 8.0 and 5.0%, for control and analog, respectively. Proportion of fatty acid turnover incorporated into triglyceride and CO{sub 2} were 14.0 and 15.0%; and 21.0 and 18.0, respectively, for control and analog. Analog increased {sup 14}C recovered in milk fat (52 vs. 36%). Plasma concentration of fatty acids, percent oxidized to CO{sub 2}, and percent of CO{sub 2} from fatty acids decreased with increasing lactation days. Milk fat percent and yield fatty acid turnover, and oxidation were positively correlated with concentration of plasma fatty acids, whereas fatty acid incorporated into plasma triglyceride was negatively correlated with fatty acid concentration. The data suggest that hepatic triglyceride secretion is not increased in early lactation; further, no effects of analog on lipid metabolism were detected.

• OSTI ID: 7059786
• Journal Information: Journal of Dairy Science; (USA), Journal Name: Journal of Dairy Science; (USA) Vol. 72:1; ISSN 0022-0302; ISSN JDSCA
• Country of Publication: United States
• Language: English

Related Subjects

553005* -- Agriculture & Food Technology-- Animal Husbandry-- (1987-)
60 APPLIED LIFE SCIENCES
AMINO ACIDS
ANIMALS
BIOLOGICAL MATERIALS
BODY FLUIDS
CARBON 14 COMPOUNDS
CARBOXYLIC ACIDS
CATTLE
COWS
DOMESTIC ANIMALS
DRUGS
FOOD
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LACTATION
LIPOTROPIC FACTORS
MAMMALS
MATERIALS
METABOLISM
METHIONINE
MILK
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
RUMINANTS
TRACER TECHNIQUES
VERTEBRATES