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Comparison of single-photon emission computed tomography with (123I)iodoamphetamine and xenon-enhanced computed tomography for assessing regional cerebral blood flow

Journal Article · · J. Cereb. Blood Flow Metab.; (United States)
; ; ; ; ; ; ; ; ;

Regional CBF (rCBF) images obtained from xenon-enhanced computed tomography (XeCT) and single-photon emission computed tomography (SPECT) with N-isopropyl-p-(/sup 123/I)iodoamphetamine (IMP) done with a rotating gamma-camera were compared in nine patients. Both XeCT and SPECT/IMP demonstrated flow abnormalities at all sites of infarction identified by CT, while detecting reduced rCBF in areas normal by CT in eight of the nine patients. All areas that were abnormal on XeCT were abnormal on the comparable SPECT/IMP images. The major advantages of XeCT are its greater resolution and potential for noninvasive quantitation of rCBF, while the major advantage of SPECT/IMP is its visualization of the entire brain on transverse, coronal, and sagittal sections.

Research Organization:
Medical College of Wisconsin, Milwaukee
OSTI ID:
7033107
Journal Information:
J. Cereb. Blood Flow Metab.; (United States), Journal Name: J. Cereb. Blood Flow Metab.; (United States) Vol. 6; ISSN JCBMD
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMPHETAMINES
ANALEPTICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BARYONS
BETA DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CAMERAS
CENTRAL NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM AGENTS
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTARY PARTICLES
ELEMENTS
EMISSION COMPUTED TOMOGRAPHY
FERMIONS
FLUIDS
GAMMA CAMERAS
GASES
HADRONS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
NERVOUS SYSTEM
NONMETALS
NUCLEI
NUCLEONS
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PROTONS
RADIOISOTOPES
RARE GASES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
SYMPATHOMIMETICS
TOMOGRAPHY
XENON