Cerebral blood flow studies using N-isopropyl I-123 p-iodoamphetamine
Twenty patients who had strokes were studied for cerebral blood perfusion abnormalities using N-isopropyl I-123 p-iodoamphetamine (IMP) and rotating dual gamma camera emission computed tomography (ECT). After a single scan, multiple transverse, coronal and sagittal section images were reconstructed with a minicomputer. In eighteen patients, the authors determined the values of regional cerebral blood flow (rCBF) in the region of interest using an image. Transmission computed tomography (CT) studies were also performed on the same day. ECT showed cerebral perfusion abnormalities in all cases, while CT showed abnormalities in only 10 cases. This technique seems to be useful for evaluating the rCBF in the deep brain.
- Research Organization:
- Fukui Medical School, Japan
- OSTI ID:
- 5664038
- Journal Information:
- Stroke; (United States), Journal Name: Stroke; (United States) Vol. 16:2; ISSN SJCCA
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
AMPHETAMINES
ANALEPTICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BLOOD FLOW
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM AGENTS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DRUGS
DYNAMIC FUNCTION STUDIES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LABELLED COMPOUNDS
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PERFUSED ORGANS
RADIOISOTOPES
SYMPATHOMIMETICS
TOMOGRAPHY
TRACER TECHNIQUES