Ultraviolet survival and sensitizing effect of caffeine in mouse hybrid cells

Journal Article · Wed Oct 01 04:00:00 EDT 1980 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575219· OSTI ID:7029937

Zampetti-Bosseler, F; Delhaise, P; Limbosch, S

In a previous paper it was reported that three hybrid cell lines between mouse lymphoma cells (L5178YS) and mouse fibroblasts (A9) were more resistant to x rays than either of the parental cells. In this work, these hybrids displayed a degree of resistance to uv light either higher than (hybrid clone 3) or similar to (hybrid clones 1 and 2) that of the more resistant parent (A9). The enhanced resistance of hybrid clone 3 to uv was related neither to changes in cell shape, ploidy, and growth rate nor to an increase in a caffeine-sensitive recovery process after uv irradiation.

• Research Organization: Univ. Libre de Bruxelles, Rhode-St-Genese, Belgium
• OSTI ID: 7029937
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 84:1; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560121* -- Radiation Effects on Cells-- External Source-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL RECOVERY
CAFFEINE
CELL CULTURES
CLONE CELLS
CONNECTIVE TISSUE CELLS
DATA
DISEASES
DOSE-RESPONSE RELATIONSHIPS
DRUGS
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
FIBROBLASTS
GROWTH
HETEROCYCLIC COMPOUNDS
HYBRIDIZATION
INFORMATION
IONIZING RADIATIONS
LYMPHOMAS
MAMMALS
MICE
MORPHOLOGY
NEOPLASMS
NUMERICAL DATA
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PLOIDY
PURINES
RADIATIONS
RADIOSENSITIVITY
RADIOSENSITIVITY EFFECTS
RECOVERY
RODENTS
SOMATIC CELLS
SURVIVAL CURVES
TUMOR CELLS
ULTRAVIOLET RADIATION
VERTEBRATES
X RADIATION
XANTHINES