Inhalation uptake of xenobiotic vapors by people. Final report, August 1986-March 1988

Technical Report · Mon Feb 29 23:00:00 EST 1988

OSTI ID:7028043

Raabe, O G

The objective of the study was to provide information on the degree to which the body absorbs inhaled toxic substances from air containing ambient concentrations. Four human subjects, two men and two women, inhaled each test compound (/sup 14/C) labeled benzene, chloroform, methyl bromide, trichlorethylene, and formaldehyde twice, once through the nose and once through the mouth. In addition, each subject inhaled benzene through the mouth while engaged in exercise. The uptake (% of inhaled) of each of the compounds was as follows: chloroform 45.6% nasal, 49.6% oral; trichloroethylene 53.9% nasal, 55.3% oral; methylbromide 55.4% nasal, 52.1% oral; benzene 60.0% nasal, 54.6% oral; formaldehyde 75.1% nasal, 86.4% oral. The uptake of benzene during exercise was 41.6%.

• Research Organization: California Univ., Davis (USA)
• OSTI ID: 7028043
• Report Number(s): PB-88-202726/XAB
• Country of Publication: United States
• Language: English

Related Subjects

500200* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AIR POLLUTION
ALDEHYDES
AROMATICS
BENZENE
CHLORINATED ALIPHATIC HYDROCARBONS
CHLOROFORM
DOCUMENT TYPES
FLUIDS
FORMALDEHYDE
GASES
HALOGENATED ALIPHATIC HYDROCARBONS
HAZARDOUS MATERIALS
HYDROCARBONS
INHALATION
INTAKE
MATERIALS
METABOLISM
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLLUTION
PROGRESS REPORT
TOXIC MATERIALS
VAPORS
XENOBIOTICS