Iron, folacin, vitamin B/sub 12/ and zinc status and immune response in elderly subjects in the Washington D. C. metropolitan area
The iron, folacin, vitamin B/sub 12/, and zinc status of a group of economically and socially disadvantaged elderly persons in the Washington Metropolitan Area was evaluated. Factors related to deficiencies of these nutrients, the relationships between the status of these nutrients and cell-mediated immunity, and the relationships of iron, folacin and vitamin B/sub 12/ status to hemoglobin levels in the subjects were also examined. It was also determined whether there were any interactions among iron, folacin, vitamin B/sub 12/ and zinc status in their relationships to cell-mediated immunity. Socio-demographic and nutritional data on the subjects were obtained using a questionnaire. Dietary data were obtained using a dietary record. A fasting blood sample was drawn and the levels of ferritin, folate and vitamin B/sub 12/, and the erythrocyte levels of folate were determined by radioassay. Plasma and hair zinc levels were determined by atomic absorption spectrophotometry. Cell-mediated immune response was determined by transformation of peripheral blood lymphocytes after stimulation by mitogens, and by allogenic lymphocytes in the mixed lymphocyte reaction.
- Research Organization:
- Howard Univ., Washington, DC (USA)
- OSTI ID:
- 7024431
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION SPECTRA
AGED ADULTS
ANIMAL CELLS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOXYLIC ACIDS
CONNECTIVE TISSUE CELLS
DIET
DRUGS
ELEMENTS
ERYTHROCYTES
FASTING
GLOBIN
HEMATINICS
HEMATOLOGIC AGENTS
HEMOGLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
IMMUNE REACTIONS
IMMUNITY
INSTITUTIONAL FACTORS
IRON
LEUKOCYTES
LYMPHOCYTES
MATERIALS
METALS
NORTH AMERICA
NUTRITIONAL DEFICIENCY
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
PORPHYRINS
PROTEINS
RADIOASSAY
SOCIO-ECONOMIC FACTORS
SOMATIC CELLS
SPECTRA
TRANSITION ELEMENTS
USA
VITAMIN B GROUP
VITAMIN B-12
VITAMINS
WASHINGTON DC
ZINC