Toxicology of complex mixtures of indoor air pollutants

Technical Report · Sun Jan 01 04:00:00 EST 1989

OSTI ID:7019659

Lewtas, J

This review focuses on strategies for assessing the toxicology of indoor air pollutant mixtures. These strategies are illustrated by reviewing the current problems and approaches to the toxicology of indoor air pollutants from three indoor source categories that make a major contribution to human exposure: environmental tobacco smoke, combustion emissions, and volatile organic compound (VOC) mixtures from materials and products. The strategies include assessment of: exposure and dosimetry, toxic effects of mixtures, causative agents in mixtures, and the predictability of toxicology from one mixture to another. Case studies from indoor air pollution are used to illustrate these strategies. Environmental tobacco smoke research on exposure and dosimetry illustrates new methods using biological markers. Unvented combustion sources such as kerosene heaters emit genotoxic incomplete combustion products and recent research is focused on identifying the genotoxic (causative) agents in these mixtures.

• Research Organization: Environmental Protection Agency, Research Triangle Park, NC (USA). Health Effects Research Lab.
• OSTI ID: 7019659
• Report Number(s): PB-90-129289/XAB; EPA--600/D-89/243
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
540120* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (1990-)
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
AIR POLLUTION
COLLOIDS
DISPERSIONS
DOCUMENT TYPES
ENVIRONMENTAL EXPOSURE
EXHAUST GASES
FLUIDS
GASEOUS WASTES
GASES
INDOOR AIR POLLUTION
MATTER
MIXTURES
ORGANIC COMPOUNDS
POLLUTION
POLLUTION SOURCES
RESIDUES
REVIEWS
SMOKES
SOLS
TOBACCO SMOKES
TOXICITY
VOLATILE MATTER
WASTES