Modeling the accumulation of three waterborne chlorinated ethanes in fathead minnows (Pimephales promelas): A physiologically based approach
Journal Article
·
· Environmental Toxicology and Chemistry; (United States)
- Environmental Protection Agency, Duluth, MN (United States). Environmental Research Lab.
- AScI Corp., Inc., Duluth, MN (United States)
A physiologically based kinetic model was used to predict the accumulation of a homologous series of chlorinated ethanes in fathead minnows (Pimephales promelas). Uptake and accumulation of these compounds are described in terms of a few fundamental physiological, morphological, and physicochemical parameters. Chemical residues in 30-d-old fathead minnows exposed to 1,1,2,2-tetrachloroethane, pentachloroethane, and hexachloroethane were used to evaluate model performance. The predicted and observed accumulations of the chlorinated ethanes were in close agreement. A quantitative assessment of the major factors regulating the exchanged of these compounds indicates that the cutaneous surface may be an important route of uptake in small fish.
- OSTI ID:
- 7017017
- Journal Information:
- Environmental Toxicology and Chemistry; (United States), Journal Name: Environmental Toxicology and Chemistry; (United States) Vol. 13:7; ISSN 0730-7268; ISSN ETOCDK
- Country of Publication:
- United States
- Language:
- English
Similar Records
Modeling the accumulation of three waterborne chlorinated ethanes in fathead minnows ( pimephales promelas'): A physiologically based approach
Toxic and teratogenic effects of hydrazine on fathead minnow (Pimephales promelas) embryos
Antimony and thallium toxicity to embryos and larvae of fathead minnows (Pimephales promelas)
Technical Report
·
Fri Dec 31 23:00:00 EST 1993
·
OSTI ID:6838179
Toxic and teratogenic effects of hydrazine on fathead minnow (Pimephales promelas) embryos
Journal Article
·
Mon Jun 01 00:00:00 EDT 1981
· Bull. Environ. Contam. Toxicol.; (United States)
·
OSTI ID:6388913
Antimony and thallium toxicity to embryos and larvae of fathead minnows (Pimephales promelas)
Journal Article
·
Tue May 01 00:00:00 EDT 1984
· Bull. Environ. Contam. Toxicol.; (United States)
·
OSTI ID:6748192
Related Subjects
54 ENVIRONMENTAL SCIENCES
540320* -- Environment
Aquatic-- Chemicals Monitoring & Transport-- (1990-)
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL ACCUMULATION
BIOLOGICAL INDICATORS
CHLORINATED ALIPHATIC HYDROCARBONS
FATHEAD MINNOW
FISHES
HALOGENATED ALIPHATIC HYDROCARBONS
MATHEMATICAL MODELS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLLUTION
SENSITIVITY
VERTEBRATES
WATER POLLUTION
540320* -- Environment
Aquatic-- Chemicals Monitoring & Transport-- (1990-)
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL ACCUMULATION
BIOLOGICAL INDICATORS
CHLORINATED ALIPHATIC HYDROCARBONS
FATHEAD MINNOW
FISHES
HALOGENATED ALIPHATIC HYDROCARBONS
MATHEMATICAL MODELS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLLUTION
SENSITIVITY
VERTEBRATES
WATER POLLUTION