Pediatric urography: comparison of metrizamide and methylglucamine diatrizoate

Journal Article · Sun Jan 01 00:00:00 EST 1984 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.150.1.6359266· OSTI ID:7014729

Robey, G; Reilly, B J; Carusi, P A; Nguyen, K B

A non-ionic contrast medium (metrizamide) was compared to an ionic agent (methylglucamine diatrizoate) for pediatric urography. Fifty children were divided into two age groups: under 5, and 5 to 10. In younger children, metrizamide gave more excellent images (19% vs. 0%) and fewer inadequate images (0% vs. 18%) than methylglucamine diatrizoate (p = 0.06). In older children, metrizamide likewise gave more excellent images (44% vs 14%) and fewer inadequate images (0% vs. 7%). The same pattern was seen when the two groups were combined (excellent, 28% vs. 8%; inadequate, 0% vs. 12%) (p = 0.05). Differences with respect to changes in hematocrit, serum osmolality, serum sodium, and SGOT were statistically significant, but not adverse reactions. In terms of both efficacy and safety, the authors conclude that metrizamide is preferred for pediatric urography.

• Research Organization: Hospital for Sick Children, Toronto, Ontario
• OSTI ID: 7014729
• Journal Information: Radiology; (United States), Vol. 150:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CONTRAST MEDIA
COMPARATIVE EVALUATIONS
SIDE EFFECTS
URINARY TRACT
BIOMEDICAL RADIOGRAPHY
CHILDREN
METRIZAMIDE
AGE GROUPS
AMIDES
BODY
DIAGNOSTIC TECHNIQUES
MEDICINE
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
RADIOLOGY
550602* - Medicine- External Radiation in Diagnostics- (1980-)