Pediatric urography: comparison of metrizamide and methylglucamine diatrizoate

Journal Article · Sat Dec 31 23:00:00 EST 1983 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.150.1.6359266· OSTI ID:7014729

Robey, G; Reilly, B J; Carusi, P A; Nguyen, K B

A non-ionic contrast medium (metrizamide) was compared to an ionic agent (methylglucamine diatrizoate) for pediatric urography. Fifty children were divided into two age groups: under 5, and 5 to 10. In younger children, metrizamide gave more excellent images (19% vs. 0%) and fewer inadequate images (0% vs. 18%) than methylglucamine diatrizoate (p = 0.06). In older children, metrizamide likewise gave more excellent images (44% vs 14%) and fewer inadequate images (0% vs. 7%). The same pattern was seen when the two groups were combined (excellent, 28% vs. 8%; inadequate, 0% vs. 12%) (p = 0.05). Differences with respect to changes in hematocrit, serum osmolality, serum sodium, and SGOT were statistically significant, but not adverse reactions. In terms of both efficacy and safety, the authors conclude that metrizamide is preferred for pediatric urography.

• Research Organization: Hospital for Sick Children, Toronto, Ontario
• OSTI ID: 7014729
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 150:1; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
AMIDES
BIOMEDICAL RADIOGRAPHY
BODY
CHILDREN
COMPARATIVE EVALUATIONS
CONTRAST MEDIA
DIAGNOSTIC TECHNIQUES
MEDICINE
METRIZAMIDE
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
RADIOLOGY
SIDE EFFECTS
URINARY TRACT