Synthesis of thyroglobulin in thyroid carcinoma patients after radioiodine therapy
Journal Article
·
· Cancer (Philadelphia); (United States)
DOI:https://doi.org/10.1002/1097-0142(19831215)52:12<2240::AID-CNCR2820521213>3.0.CO;2-0·
OSTI ID:7013001
Endogenously radioiodinated thyroglobulin (Tg) and the serum concentration of Tg have been measured in patients with metastatic thyroid carcinoma after therapeutic doses of radioiodine. Serial samples of blood were analyzed for both these parameters over a period of 10 to 22 days. The specific activity of Tg (cpm/ng) was calculated for each sample. Among the six patients studied, three showed constant specific activity. The specific activity of the other three fell, indicating the entering of newly synthesized Tg into the circulation. The respective amounts of Tg entering into the circulation in these three patients were 120, 852, and 20,935 ng/ml serum/day.
- Research Organization:
- Tata Memorial Center Annexe, Parel, Bombay, India
- OSTI ID:
- 7013001
- Journal Information:
- Cancer (Philadelphia); (United States), Journal Name: Cancer (Philadelphia); (United States) Vol. 52:12; ISSN CANCA
- Country of Publication:
- United States
- Language:
- English
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Journal Article
·
Tue Jun 01 00:00:00 EDT 1982
· Cancer (Philadelphia); (United States)
·
OSTI ID:7055168
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Journal Article
·
Mon Nov 30 23:00:00 EST 1987
· J. Nucl. Med.; (United States)
·
OSTI ID:5721364
Critical evaluation of serum thyroglobulin levels and I-131 scans in post-therapy patients with differentiated thyroid carcinoma: concise communication
Journal Article
·
Sun Feb 28 23:00:00 EST 1982
· J. Nucl. Med.; (United States)
·
OSTI ID:5176664
Related Subjects
560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOSYNTHESIS
BLOOD SERUM
BODY
CARCINOMAS
CHEMICAL ANALYSIS
DISEASES
DISTRIBUTION
ENDOCRINE GLANDS
GLANDS
GLOBULINS
IODINE ISOTOPES
ISOTOPES
MEDICINE
METASTASES
NEOPLASMS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PROTEINS
RADIOLOGY
RADIOTHERAPY
SYNTHESIS
THERAPY
THYROGLOBULIN
THYROID
TIME DEPENDENCE
TISSUE DISTRIBUTION
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOSYNTHESIS
BLOOD SERUM
BODY
CARCINOMAS
CHEMICAL ANALYSIS
DISEASES
DISTRIBUTION
ENDOCRINE GLANDS
GLANDS
GLOBULINS
IODINE ISOTOPES
ISOTOPES
MEDICINE
METASTASES
NEOPLASMS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PROTEINS
RADIOLOGY
RADIOTHERAPY
SYNTHESIS
THERAPY
THYROGLOBULIN
THYROID
TIME DEPENDENCE
TISSUE DISTRIBUTION