Liquid-phase chromatography detector

Patent · Mon Nov 07 23:00:00 EST 1983

OSTI ID:7004222

Voigtman, E G; Winefordner, J D; Jurgensen, A R

A liquid-phase chromatography detector comprises a flow cell having an inlet tubular conduit for receiving a liquid chromatographic effluent and discharging it as a flowing columnar stream onto a vertically adjustable receiving surface spaced apart from and located vertically below and in close proximity to the discharge end of the tubular conduit; a receiver adapted to receive liquid overflowing from the receiving surface; an exit conduit for continuously removing liquid from the receiver; a light source for focusing fluorescence-producing light pulses on the flowing columnar stream as it passes from the outlet of the conduit to the receiving surface and a fluorescence detector to detect the produced fluorescence; a source of light pulse for producing acoustic waves in the columnar stream as it passes from the conduit outlet to the receiving surface; and a piezoelectric transducer adapted to detect those waves; and a source of bias voltage applied to the inlet tubular conduit and adapted to produce ionization of the liquid flowing through the flow cell so as to produce photocurrents therein and an electrical system to detect and record the photocurrents. This system is useful in separating and detecting individual chemical compounds from mixtures thereof. 5 figs.

• Research Organization: University of Florida
• Sponsoring Organization: United States Department of Energy
• DOE Contract Number: AS05-78OR06022
• Assignee: Univ. of Florida, Gainesville, FL (United States)
• Patent Number(s): US 4413504; A
• Application Number: PPN: US 6-382633
• OSTI ID: 7004222
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102 -- Chemical & Spectral Procedures
400105* -- Separation Procedures
CHEMICAL ANALYSIS
CHROMATOGRAPHY
DESIGN
DISPERSIONS
FLUID FLOW
FLUORESCENCE
IONIZATION
LIQUID COLUMN CHROMATOGRAPHY
LIQUID FLOW
LUMINESCENCE
MEASURING INSTRUMENTS
MIXTURES
MONITORS
SEPARATION PROCESSES
SOUND WAVES