Alteration in carboxyhemoglobin concentrations during exposure to 9 ppm carbon monoxide for 8 hours at sea level and 2134 m altitude in a hypobaric chamber
- Univ. of California, Santa Barbara (USA)
Seventeen non-smoking young men served as subjects to determine the alteration in carboxyhemoglobin (COHb) concentrations during exposure to 0 or 9 ppm carbon monoxide for 8 hours (CO) at sea level or an altitude of 2134 meters (7000 feet) in a hypobaric chamber. Nine subjects rested during the exposure and 8 exercised for 10 minutes of each exposure hour at a mean ventilation of 25 L (BTPS). All subjects performed a maximal aerobic capacity test at the completion of their respective exposures. Carboxyhemoglobin concentrations fell in all subjects during their exposures to 0 ppm CO at sea level or 2134 m. During the 8-h exposures to 9 ppm CO, COHb rose linearly from approximately 0.2 percent to 0.7 percent. No significant differences in uptake were found whether the subjects were resting or intermittently exercising during their 8-h exposures. COHb levels attained were similar at both sea level and 2134 m. Maximal aerobic capacity was reduced approximately 7-10 percent consequent to altitude exposure during 0 ppm CO exposures. These values were not altered following exposure for 8 h to 9 ppm CO in either the resting or exercising subjects.
- OSTI ID:
- 7001045
- Journal Information:
- JAPCA, the International Journal of Air Pollution Control and Hazardous Waste Management; (USA), Journal Name: JAPCA, the International Journal of Air Pollution Control and Hazardous Waste Management; (USA) Vol. 39:10; ISSN JIJME; ISSN 0894-0630
- Country of Publication:
- United States
- Language:
- English
Similar Records
Absence of symptoms with carboxyhemoglobin levels of 16-23%
Effects of low-level carbon monoxide exposure on resting and exercise-induced ventricular arrhythmias in patients with coronary artery disease and no baseline ectopy
Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALTITUDE
ANIMALS
BIOLOGICAL EFFECTS
BIOSYNTHESIS
CARBON COMPOUNDS
CARBON MONOXIDE
CARBON OXIDES
CARBOXYHEMOGLOBIN
CHALCOGENIDES
EXERCISE
MAMMALS
MAN
METABOLISM
OXIDES
OXYGEN COMPOUNDS
PRIMATES
SYNTHESIS
VERTEBRATES