Effect of dissolved carbon dioxide on penicillin fermentations: mycelial growth and penicillin production. [Penicillium chrysogenum]

Journal Article · Wed Jan 01 00:00:00 EST 1986 · Biotechnol. Bioeng.; (United States)

DOI:https://doi.org/10.1002/bit.260280506· OSTI ID:6997430

Ho, C S; Smith, M D

The effect of dissolved carbon dioxide on the specific growth rate and the penicillin production rate of Penicillium chrysogenum was examined experimentally. The dissolved carbon dioxide was found to inhibit the specific growth rate and the penicillin production rate when the aerated submerged penicillin fermentation was exposed to influent gases of 12.6 and 20% carbon dioxide, respectively. Upon exposure to influent gases of 3 and 5% carbon dioxide, no pronounced metabolic inhibition was noted.

• Research Organization: State Univ. of New York, Buffalo
• OSTI ID: 6997430
• Journal Information: Biotechnol. Bioeng.; (United States), Vol. 28:5
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CARBON DIOXIDE
TOXICITY
PENICILLIUM
GROWTH
METABOLISM
FERMENTATION
INHIBITION
BIOCONVERSION
CARBON COMPOUNDS
CARBON OXIDES
CHALCOGENIDES
FUNGI
OXIDES
OXYGEN COMPOUNDS
PLANTS
560300* - Chemicals Metabolism & Toxicology