Effect of dissolved carbon dioxide on penicillin fermentations: mycelial growth and penicillin production. [Penicillium chrysogenum]

Journal Article · Tue Dec 31 23:00:00 EST 1985 · Biotechnol. Bioeng.; (United States)

DOI:https://doi.org/10.1002/bit.260280506· OSTI ID:6997430

Ho, C S; Smith, M D

The effect of dissolved carbon dioxide on the specific growth rate and the penicillin production rate of Penicillium chrysogenum was examined experimentally. The dissolved carbon dioxide was found to inhibit the specific growth rate and the penicillin production rate when the aerated submerged penicillin fermentation was exposed to influent gases of 12.6 and 20% carbon dioxide, respectively. Upon exposure to influent gases of 3 and 5% carbon dioxide, no pronounced metabolic inhibition was noted.

• Research Organization: State Univ. of New York, Buffalo
• OSTI ID: 6997430
• Journal Information: Biotechnol. Bioeng.; (United States), Journal Name: Biotechnol. Bioeng.; (United States) Vol. 28:5; ISSN BIBIA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOCONVERSION
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CHALCOGENIDES
FERMENTATION
FUNGI
GROWTH
INHIBITION
METABOLISM
OXIDES
OXYGEN COMPOUNDS
PENICILLIUM
PLANTS
TOXICITY