Drinking water and health. Volume 6. Final report

Technical Report · Wed Jan 01 04:00:00 EST 1986

OSTI ID:6995204

Thomas, R D

The volume reviews the state of the art in the developing field of risk assessment and provides some risk assessment for drinking water exposure to 14 compounds of interest to the EPA as the agency develops its regulatory program. Reflecting the tendency of past toxicological studies to focus on cancer as the main health effect of concern, most of the risk assessments in the report were estimated for carcinogenicity. Wherever data were adequate, however, the committee also developed risk assessments for noncancer end points. The report assesses methods for using epidemiological data in conducting risk assessments and methods for extrapolating results of laboratory animal inhalation studies to estimate human risk from ingestion. The reports describes mathematical modeling approaches currently available or under development of the assessment of noncancer risks.

• Research Organization: National Research Council, Washington, DC (United States)
• OSTI ID: 6995204
• Report Number(s): PB-92-223130/XAB; CNN: EPA-68-01-6371
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
540220* -- Environment
Terrestrial-- Chemicals Monitoring & Transport-- (1990-)
560300 -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOLOGICAL MODELS
CARCINOGENESIS
CONTAMINATION
DISEASES
DOSE-RESPONSE RELATIONSHIPS
DRINKING WATER
EPIDEMIOLOGY
HYDROGEN COMPOUNDS
LABORATORY ANIMALS
MATHEMATICAL MODELS
NEOPLASMS
NERVOUS SYSTEM
OXYGEN COMPOUNDS
PATHOGENESIS
POLLUTANTS
POLLUTION
RISK ASSESSMENT
TOXICITY
WATER
WATER POLLUTION