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Changes of lipofuscin-like pigments in erythrocytes and spleen after whole-body gamma irradiation of rats

Journal Article · · Radiation Research; (USA)
DOI:https://doi.org/10.2307/3577710· OSTI ID:6992342
; ;  [1]
  1. Charles Univ., Praha (Czechoslovakia)
Whole-body gamma irradiation of rats induced the formation of lipofuscin-like pigments in erythrocytes. Erythrocytes that were damaged by oxidation were scavenged in the spleen, and lipofuscin-like pigments were transferred from erythrocytes to the spleen during this process. The time course of lipofuscin-like pigments in erythrocytes and spleen indicates that the pigments were not induced by the action of free radicals produced by ionizing radiation but rather were a sequela of postirradiation metabolic changes.
OSTI ID:
6992342
Journal Information:
Radiation Research; (USA), Journal Name: Radiation Research; (USA) Vol. 120:2; ISSN RAREA; ISSN 0033-7587
Country of Publication:
United States
Language:
English