Comparison of staging methods for Hodgkin's disease in children

Journal Article · Wed Oct 01 04:00:00 EDT 1986 · Arch. Surg. (Chicago); (United States)

DOI:https://doi.org/10.1001/archsurg.1986.01400100031005· OSTI ID:6990888

Lally, K P; Arnstein, M; Siegel, S; Miller, J H; Gilsanz, V; Ettinger, L; Atkinson, J B

Potential long-term complications of radiotherapy and chemotherapy in the pediatric patient with Hodgkin's disease necessitate accurate staging. To determine the accuracy of abdominal computed tomography (CT) and gallium citrate Ga 67 scans in staging Hodgkin's disease, we reviewed the charts of all children with Hodgkin's disease seen at Childrens Hospital of Los Angeles from 1975 to 1985. Patients with pathologically proved stage IV disease (ie, bone marrow involvement) and those who only underwent staging laparotomy were excluded. A total of 40 children underwent staging by laparotomy and staging by abdominal CT and/or /sup 67/Ga scan. The CT and /sup 67/Ga scans were reviewed by radiologists in a blinded manner and compared with the results of a formal staging laparotomy. Of the 38 patients whose disease was staged with /sup 67/Ga scan, disease in ten was understaged and in four overstaged, for a 37% incorrect staging rate. Of the 14 patients whose disease was staged by CT scan, disease in three was understaged and in one overstaged, for a 29% incorrect staging rate. In view of the inaccuracy of noninvasive studies and the impact of incorrect staging on treatment, we recommend that a staging laparotomy be performed in all children with Hodgkin's disease who are not proved to have stage IV disease.

• Research Organization: Childrens Hospital of Los Angeles, CA
• OSTI ID: 6990888
• Journal Information: Arch. Surg. (Chicago); (United States), Journal Name: Arch. Surg. (Chicago); (United States) Vol. 10; ISSN ARSUA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ABDOMEN
AGE GROUPS
BETA DECAY RADIOISOTOPES
BODY
BODY AREAS
CHEMOTHERAPY
CHILDREN
CLASSIFICATION
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM ISOTOPES
HODGKINS DISEASE
INTERMEDIATE MASS NUCLEI
ISOTOPES
LYMPHOMAS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SCINTISCANNING
SURGERY
THERAPY
TOMOGRAPHY