Chemical scoring by a rapid screening of hazard (RASH) method

Journal Article · Tue Mar 01 04:00:00 EST 1988 · Risk Anal.; (United States)

DOI:https://doi.org/10.1111/j.1539-6924.1988.tb01157.x· OSTI ID:6970749

Jones, T D; Walsh, P J; Watson, A P; Owen, B A; Barnthouse, L W; Sanders, D A

A rapid screening of hazard method (RASH) is presented for deriving relative potency estimates for hazardous substances. The method utilizes data from any available toxicological database such as the Registry of Toxic Effects of Chemical Substances (RTECS) or EPA's GENE-TOX database on genetic activity profiles. The method has been applied to derive relative potency values and permissible environmental concentrations for 278 chemicals. The derived values have been compared with recommendations of expert committees where possible, and substantial agreement is found.

• Research Organization: Oak Ridge National Lab., TN (USA)
• OSTI ID: 6970749
• Journal Information: Risk Anal.; (United States), Journal Name: Risk Anal.; (United States) Vol. 8:1; ISSN RIAND
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
DOSE-RESPONSE RELATIONSHIPS
HAZARDOUS MATERIALS
MATERIALS
MAXIMUM PERMISSIBLE EXPOSURE
RECOMMENDATIONS
RISK ASSESSMENT
SAFETY STANDARDS
SCREENING
STANDARDS
XENOBIOTICS