Preliminary assessment of the relative toxicity of copper naphthenate acute studies. Phase 2. May 1984-June 1986. Study report
Technical Report
·
OSTI ID:6968657
A series of studies was performed in laboratory animals and biological systems to determine the relative toxicities of copper naphthenate and a wood-preservative formulation thereof. The studies included primary skin and eye irritation, acute oral and dermal toxicity, skin sensitization, saturated vapor inhalation, mutagenicity screening, dominant lethal studies, avian toxicity and aquatic toxicity. The results of this testing indicated that Cunapsol 5 has the potential to cause severe irritation by the dermal and ocular routes. Copper naphthenate and Cunapsol 5 are of low toxicity by the oral route. Cunapsol 5 does cause death when applied to the skin of rabbits at moderate dosage levels. Recommendations provide for the wearing of protective eyewear, gloves, and coveralls by individuals involved in presentative treatment operations and that these operations should be carried out in well-ventilated areas. Due to the high degree of toxicity of copper naphthenate in one fish species, it was further recommended that disposal of excess preservative materials should be done in an environmentally acceptable manner.
- Research Organization:
- Army Environmental Hygiene Agency, Aberdeen Proving Ground, MD (USA)
- OSTI ID:
- 6968657
- Report Number(s):
- AD-A-190851/6/XAB; USAEHA-75-51-0497-87
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550900 -- Pathology
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKANES
ANIMALS
AQUATIC ORGANISMS
BIOLOGY
BIRDS
CLOTHING
COPPER COMPOUNDS
CYCLOALKANES
DEATH
DOCUMENT TYPES
FISHES
FLUIDS
GASES
GLOVES
HYDROCARBONS
LABORATORY ANIMALS
MAMMALS
ORGANIC COMPOUNDS
PRESERVATIVES
PROGRESS REPORT
PROTECTIVE CLOTHING
RABBITS
SATURATION
TOXICITY
TRANSITION ELEMENT COMPOUNDS
VAPORS
VENTILATION
VERTEBRATES
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKANES
ANIMALS
AQUATIC ORGANISMS
BIOLOGY
BIRDS
CLOTHING
COPPER COMPOUNDS
CYCLOALKANES
DEATH
DOCUMENT TYPES
FISHES
FLUIDS
GASES
GLOVES
HYDROCARBONS
LABORATORY ANIMALS
MAMMALS
ORGANIC COMPOUNDS
PRESERVATIVES
PROGRESS REPORT
PROTECTIVE CLOTHING
RABBITS
SATURATION
TOXICITY
TRANSITION ELEMENT COMPOUNDS
VAPORS
VENTILATION
VERTEBRATES