Lyme carditis. Electrophysiologic and histopathologic study
To further define the nature of Lyme carditis, electrophysiologic study and endomyocardial biopsy were performed in a patient with Lyme disease, whose principal cardiac manifestation was high-degree atrioventricular block. Intracardiac recording demonstrated supra-Hisian block and complete absence of an escape mechanism. Gallium 67 scanning demonstrated myocardial uptake, and right ventricular endomyocardial biopsy revealed active lymphocytic myocarditis. A structure compatible with a spirochetal organism was demonstrated in one biopsy specimen. It is concluded that Lyme disease can produce active myocarditis, as suggested by gallium 67 imaging and confirmed by endomyocardial biopsy. Furthermore, the presence of high-grade atrioventricular block in this disease requires aggressive management with temporary pacemaker and corticosteroid therapy.
- Research Organization:
- Chicago College of Osteopathic Medicine, IL
- OSTI ID:
- 6965229
- Journal Information:
- Am. J. Med.; (United States), Journal Name: Am. J. Med.; (United States) Vol. 5; ISSN AJMEA
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BACTERIA
BETA DECAY RADIOISOTOPES
BIOPSY
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ELECTROPHYSIOLOGY
ETIOLOGY
GALLIUM 67
GALLIUM ISOTOPES
HEART
INFECTIOUS DISEASES
INTERMEDIATE MASS NUCLEI
ISOTOPES
MICROORGANISMS
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOGENESIS
PATIENTS
PHYSIOLOGY
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SPIROCHAETES
UPTAKE