Measurements and monitoring of phototherapy in newborn jaundice
Journal Article
·
· Med. Instrum. (Arlington, Va.); (United States)
OSTI ID:6942553
Hyperbilirubinemia in the newborn (neonatal jaundice) may cause irreversible brain damage if plasma concentrations of bilirubin exceed the number of binding sites on albumin and other blood components. Phototherapy or exchange transfusions to prevent the excessive rise in concentration of the pigment should be instituted in appropriate clinical situations. In phototherapy, the jaundiced infant is exposed to visible light containing the wavelength (about 450 nm) bilirubin will absorb. Because bilirubin is quite photolabile and will readily isomerize in vivo, it is rapidly converted to excretable forms. The effectiveness of this therapy, however, depends upon the maintenance of adequate radiant flux in the required wavelength. Energy output and spectral distributions of phototherapy lamps must be measured. The long-term effects of irradiation of newborn infants over several days are not yet known.
- OSTI ID:
- 6942553
- Journal Information:
- Med. Instrum. (Arlington, Va.); (United States), Journal Name: Med. Instrum. (Arlington, Va.); (United States) Vol. 16:3; ISSN MLISB
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
AZOLES
BILIRUBIN
CARBOXYLIC ACIDS
CHEMICAL REACTIONS
CLEARANCE
ELECTROMAGNETIC RADIATION
EVALUATION
EXCRETION
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
JAUNDICE
MEDICINE
NEONATES
NUCLEAR MEDICINE
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PATHOLOGICAL CHANGES
PHOTOCHEMICAL REACTIONS
PHOTOSENSITIVITY
PIGMENTS
PYRROLES
RADIATIONS
RADIOLOGY
RADIOTHERAPY
SENSITIVITY
SYMPTOMS
THERAPY
VISIBLE RADIATION
62 RADIOLOGY AND NUCLEAR MEDICINE
AZOLES
BILIRUBIN
CARBOXYLIC ACIDS
CHEMICAL REACTIONS
CLEARANCE
ELECTROMAGNETIC RADIATION
EVALUATION
EXCRETION
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
JAUNDICE
MEDICINE
NEONATES
NUCLEAR MEDICINE
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PATHOLOGICAL CHANGES
PHOTOCHEMICAL REACTIONS
PHOTOSENSITIVITY
PIGMENTS
PYRROLES
RADIATIONS
RADIOLOGY
RADIOTHERAPY
SENSITIVITY
SYMPTOMS
THERAPY
VISIBLE RADIATION