Number of osteogenic precursor cells in bone marrow and their multiplication in culture
Journal Article
·
· Bull. Exp. Biol. Med. (Engl. Transl.); (United States)
OSTI ID:6940968
The aim of this investigation was to study which fraction of clonogenic cells (CFU /SUB f/ ) isolated from bone marrow possesses osteogenic properties and whether the number of osteogenic precursor cells increases during culture of bone marrow fibroblasts. Experiments were carried out on Californian rabbits. In the experiments, allogeneic bone marrow cells were irradiated in a dose of 6000 rads. The results described show that the proliferative potential of CFU /SUB f/ is extremely great and that the progeny of CFU /SUB f/ preserve the properties of osteogenic precursors during cell multiplication. Osteogenic stem CFU /SUB f/ account for not less than 4% of all clonogenic bone marrow stromal cells.
- Research Organization:
- N.F. Gamaleya Institute of Epidemiology, Acad. of Med. Sci., Moscow
- OSTI ID:
- 6940968
- Journal Information:
- Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Journal Name: Bull. Exp. Biol. Med. (Engl. Transl.); (United States) Vol. 98:11; ISSN BEXBA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Question of bone marrow stromal fibroblast traffic
Osteogenic precursor cells in reparative osteogenesis
Radiosensitivity of precursor stromal cells of human bone marrow when exposed to radiation in vitro in bone and cell suspension, and the modifying effect of hypoxia
Journal Article
·
Mon Dec 31 23:00:00 EST 1984
· Ann. N.Y. Acad. Sci.; (United States)
·
OSTI ID:5737701
Osteogenic precursor cells in reparative osteogenesis
Journal Article
·
Fri Oct 31 23:00:00 EST 1986
· Bull. Exp. Biol. Med. (Engl. Transl.); (United States)
·
OSTI ID:5563576
Radiosensitivity of precursor stromal cells of human bone marrow when exposed to radiation in vitro in bone and cell suspension, and the modifying effect of hypoxia
Journal Article
·
Mon Oct 01 00:00:00 EDT 1979
· Radiobiology (USSR) (Engl. Transl.); (United States)
·
OSTI ID:5663410
Related Subjects
550300 -- Cytology
560120* -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BONE MARROW CELLS
CELL CULTURES
CELL PROLIFERATION
CFU
CLONE CELLS
COLONY FORMATION
CONNECTIVE TISSUE CELLS
FIBROBLASTS
IRRADIATION
MAMMALS
PRECURSOR
RABBITS
RADIATION EFFECTS
SOMATIC CELLS
TRANSPLANTS
VERTEBRATES
560120* -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BONE MARROW CELLS
CELL CULTURES
CELL PROLIFERATION
CFU
CLONE CELLS
COLONY FORMATION
CONNECTIVE TISSUE CELLS
FIBROBLASTS
IRRADIATION
MAMMALS
PRECURSOR
RABBITS
RADIATION EFFECTS
SOMATIC CELLS
TRANSPLANTS
VERTEBRATES