Diagnosis of recurrent hyperparathyroidism: comparison of MR imaging and other imaging techniques

Journal Article · Sun May 01 04:00:00 EDT 1988 · AJR, Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.150.5.1027· OSTI ID:6938839

Auffermann, W; Gooding, G A; Okerlund, M D; Clark, O H; Thurnher, S; Levin, K E; Higgins, C B

Several reports have indicated good results with MR imaging of hyperparathyroidism. However, its use in recurrent hyperparathyroidism has not been assessed separately. Thirty patients with recurrent hyperparathyroidism were evaluated by MR with both T1- and T2-weighted images. Twenty-six and 23 of these patients, respectively, also had thallium-201 scintigraphy and high-resolution sonography. For the 28 patients who eventually had surgical exploration and histologic evidence of adenoma (21 cases) or hypoplasia (seven cases), MR accurately located abnormal parathyroid glands in 75% evaluated prospectively and 89% evaluated retrospectively. Scintigraphy located 68% prospectively and 76% retrospectively. Sonography detected 57% prospectively and 67% retrospectively. For patients undergoing three studies, the prospective and retrospective detection rate was significantly better (p less than .05) for MR compared with sonography but was not significantly different for MR and scintigraphy. MR detected three of four mediastinal adenomas evaluated prospectively and retrospectively. One false-positive case was seen with MR, one with scintigraphy, and one with sonography. Thus, MR can be used to locate abnormal parathyroid tissue at a rate equal to or better than scintigraphy or sonography.

• Research Organization: Univ. of California Medical School, San Francisco (USA)
• OSTI ID: 6938839
• Journal Information: AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 150:5; ISSN AAJRD
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
BETA DECAY RADIOISOTOPES
BODY
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
HEAVY NUCLEI
HYPERPARATHYROIDISM
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NEOPLASMS
NMR IMAGING
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PARATHYROID GLANDS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
ULTRASONOGRAPHY