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Asbestos exposure and gastrointestinal malignancy review and meta-analysis

Technical Report ·
OSTI ID:6936939
;
The epidemiologic literature linking asbestos exposure with gastrointestinal malignancy is reviewed. Problems in comparing studies are discussed, appropriate strategies for comparison are developed, and study results are pooled using a model which accounts for both intrastudy and interstudy variability. Stratification of cohorts by dose reveals that significant asbestos exposure, as indicated by a lung cancer standardized mortality ratio (SMR) of at least 200, is associated with an elevated gastrointestinal cancer SMR for five or six end points examined.
Research Organization:
Harvard Univ., Boston, MA (USA). School of Public Health
OSTI ID:
6936939
Report Number(s):
PB-90-232216/XAB
Country of Publication:
United States
Language:
English

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Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ASBESTOS
CARCINOGENESIS
DIGESTIVE SYSTEM
DISEASES
EPIDEMIOLOGY
GASTROINTESTINAL TRACT
MAMMALS
MAN
MORTALITY
NEOPLASMS
OCCUPATIONAL EXPOSURE
PATHOGENESIS
PRIMATES
TABLES
VERTEBRATES