Magnetic resonance imaging diagnosis of disseminated necrotizing leukoencephalopathy

Journal Article · Thu Jan 01 00:00:00 EST 1987 · CT: J. Comput. Tomography; (United States)

DOI:https://doi.org/10.1016/0149-936X(87)90031-2· OSTI ID:6936108

Atlas, S W; Grossman, R I; Packer, R J; Goldberg, H I; Hackney, D B; Zimmerman, R A; Bilaniuk, L T

Disseminated necrotizing leukoencephalopathy is a rare syndrome of progressive neurologic deterioration seen most often in patients who have received central nervous system irradiation combined with intrathecal or systemic chemotherapy in the treatment or prophylaxis of various malignancies. Magnetic resonance imaging was more sensitive than computed tomography in detecting white matter abnormalities in the case of disseminated necrotizing leukoencephalopathy reported here. Magnetic resonance imaging may be useful in diagnosing incipient white matter changes in disseminated necrotizing leukoencephalopathy, thus permitting early, appropriate therapeutic modifications.

• Research Organization: Hospital of the Univ. of Pennsylvania, Philadelphia
• OSTI ID: 6936108
• Journal Information: CT: J. Comput. Tomography; (United States), Vol. 1
• Country of Publication: United States
• Language: English

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