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Magnetic resonance imaging diagnosis of disseminated necrotizing leukoencephalopathy

Journal Article · · CT: J. Comput. Tomography; (United States)

Disseminated necrotizing leukoencephalopathy is a rare syndrome of progressive neurologic deterioration seen most often in patients who have received central nervous system irradiation combined with intrathecal or systemic chemotherapy in the treatment or prophylaxis of various malignancies. Magnetic resonance imaging was more sensitive than computed tomography in detecting white matter abnormalities in the case of disseminated necrotizing leukoencephalopathy reported here. Magnetic resonance imaging may be useful in diagnosing incipient white matter changes in disseminated necrotizing leukoencephalopathy, thus permitting early, appropriate therapeutic modifications.

Research Organization:
Hospital of the Univ. of Pennsylvania, Philadelphia
OSTI ID:
6936108
Journal Information:
CT: J. Comput. Tomography; (United States), Journal Name: CT: J. Comput. Tomography; (United States) Vol. 1; ISSN CJCTD
Country of Publication:
United States
Language:
English