Impaired exercise performance and pulmonary function in elite cyclists during low-level ozone exposure in a hot environment

Journal Article · Wed Oct 01 04:00:00 EDT 1986 · Am. Rev. Respir. Dis.; (United States)

OSTI ID:6933628

Gong, H Jr; Bradley, P W; Simmons, M S; Tashkin, D P

We evaluated the effects of low concentrations of ozone on the exercise performance and pulmonary function of 17 top-caliber endurance cyclists under conditions simulating competition and realistic temperature (3/sup 0/C). Each subject was randomly exposed to filtered air (FA), 0.12 and 0.20 ppm O/sub 3/ on separate days in an environmental chamber. Each subject attempted to maintain submaximal exercise on a cycle ergometer equivalent to approximately 70% of maximal oxygen consumption (VO/sub 2/max) for 60 min, followed by incremented (maximal) exercise until exhaustion. During submaximal exercise, average minute ventilation (VE) (89 L/min), VO/sub 2/ (51 ml/min/kg or 72% VO/sub 2/max), work load (260 W), and work time (57 min) were similar across all exposures. During maximal exercise, average peak VE (150 L/min), VO/sub 2/ (68 ml/min/kg), work load (382 W), and ride time (263 s) were similar between 0.12 ppm O/sub 3/ and FA. However, significant reductions in peak VE (18%), VO/sub 2/ (16%), tidal volume (22%), work load (8%), and ride time (30%) occurred in 0.20 ppm O/sub 3/ compared with those in FA. Postexercise decrements in forced expired volume in one second (FEV1) averaged 5.6% and 21.6% in 0.12 and 0.20 ppm O/sub 3/, respectively. Ozone-related symptoms were mild in 0.12 ppm O/sub 3/ but intensified and probably limited maximal performance in 13 subjects in 0.20 ppm O/sub 3/. Changes in carbon monoxide diffusing capacity (adjusted for alveolar volume) were not significant across exposures. Nine subjects showed histamine hyperresponsiveness (i.e., greater than 20% decrease from the control postdiluent FEV1) after exposure to 0.20 ppm O/sub 3/ as compared with 1 subject in 0.12 ppm O/sub 3/.(ABSTRACT TRUNCATED AT 250 WORDS)

• OSTI ID: 6933628
• Journal Information: Am. Rev. Respir. Dis.; (United States), Journal Name: Am. Rev. Respir. Dis.; (United States) Vol. 4; ISSN ARDSB
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BODY
CARBON COMPOUNDS
CARBON MONOXIDE
CARBON OXIDES
CHALCOGENIDES
DYNAMIC FUNCTION STUDIES
EXERCISE
HAZARDS
HEALTH HAZARDS
LUNGS
MAMMALS
MAN
ORGANS
OXIDES
OXYGEN COMPOUNDS
OZONE
PERFORMANCE
PRIMATES
RESPIRATORY SYSTEM
SMOG
TEMPERATURE EFFECTS
TOXICITY
VERTEBRATES