Role of postoperative local or regional irradiation in the treatment of Stage 1 ovarian cancer
Journal Article
·
· Radiology; (United States)
- Harvard Medical School, Boston, MA
Histological grade and cell type were major prognostic factors in a retrospective study of 63 patients with Stage I epithelial carcinoma of the ovary. Grading by architectural pattern seemed to predict relapse better than cytological grading. With serous, mucinous, and endometrioid cystadenocarcinomas, relapses increased with higher grades. Relapse occurred in none of 18 tumors of borderline malignancy, 2 of 27 (7%) with Grade I or II tumor, and 4 of 6 (67%) with Grade III. The upper abdomen and pelvis were both at risk. Because most recurrences were limited to the peritoneal surface in Grade III serous, mucinous, and endometrioid carcinoma, local and regional radiation therapy are justified; postoperative therapy is not recommended for borderline or Grade I tumors unless ascites or cytological evidence of peritoneal disease is present. Clear-cell carcinoma was uncommon and unfavorable; of 12 cases, 5 involved relapse, with 3 recurrences developing outside the abdomen.
- OSTI ID:
- 6931614
- Journal Information:
- Radiology; (United States), Journal Name: Radiology; (United States) Vol. 142:3; ISSN RADLA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
550603 -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCELERATORS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BODY AREAS
CARCINOMAS
CHEMOTHERAPY
COLLOIDS
DAYS LIVING RADIOISOTOPES
DISEASES
DISPERSIONS
EVALUATION
FEMALE GENITALS
FRACTIONATED IRRADIATION
GONADS
HISTOLOGY
IRRADIATION
ISOTOPES
LIGHT NUCLEI
LINEAR ACCELERATORS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
OVARIES
PATHOLOGY
PATIENTS
PELVIS
PHOSPHORUS 32
PHOSPHORUS ISOTOPES
RADIOCOLLOIDS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY
550603 -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCELERATORS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
BODY AREAS
CARCINOMAS
CHEMOTHERAPY
COLLOIDS
DAYS LIVING RADIOISOTOPES
DISEASES
DISPERSIONS
EVALUATION
FEMALE GENITALS
FRACTIONATED IRRADIATION
GONADS
HISTOLOGY
IRRADIATION
ISOTOPES
LIGHT NUCLEI
LINEAR ACCELERATORS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
OVARIES
PATHOLOGY
PATIENTS
PELVIS
PHOSPHORUS 32
PHOSPHORUS ISOTOPES
RADIOCOLLOIDS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY