Radiation necrosis of the mandible: a 10 year study. Part II. Dental factors; onset, duration and management of necrosis

Journal Article · Thu May 01 04:00:00 EDT 1980 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(80)90381-8· OSTI ID:6926030

Murray, C G; Herson, J; Daly, T E; Zimmerman, S

In a review of patients receiving radiation for cancer in the oral region the rate of radiation necrosis of the mandible was found to be similar for patients who had dental extractions before radiation therapy and for the remainder of the dentate population. It was suggested that diseased teeth should be removed prior to irradiation and sufficient healing time should be allowed. Teeth should not be extracted after irradiation. Dental prostheses can be provided for most irradiated patients if adequate care is exercised. The probability of necrosis commencing was highest three to twelve months after the start of therapy; it diminished gradually after that period. The duration of necrosis was depicted as an exponential curve with a constant probability of necrosis termination at each time point after onset. In 46.8% of the patients in study II (1971-1975), the necrosis was healed by conservative means. This was a significant increase over study I (1966-1969), and a complementary reduction in the necessity for surgical intervention was also found.

• Research Organization: Univ. of Texas System Cancer Center, Houston
• OSTI ID: 6926030
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 6:5; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DATA
DENTISTRY
DIGESTIVE SYSTEM
DISEASES
EXPERIMENTAL DATA
INFORMATION
INJURIES
JAW
LOCAL RADIATION EFFECTS
MEDICINE
NECROSIS
NUCLEAR MEDICINE
NUMERICAL DATA
ORAL CAVITY
ORGANS
OSTEORADIONECROSIS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOINDUCTION
RADIOLOGY
RADIOTHERAPY
RESPONSE MODIFYING FACTORS
SIDE EFFECTS
SKELETAL DISEASES
SKELETON
SKULL
TEETH
THERAPY
TIME DEPENDENCE