Walk-through survey report of Burns-Biotec Laboratories, Omaha, Nebraska, November 24-25, 1980

Technical Report · Sun Mar 15 04:00:00 EST 1981

OSTI ID:6924620

Elliott, L; Pauker, S

In efforts to understand risks to workers engaged in research with recombinant DNA processes and associated industries, a walk-through survey was conducted at Burns-Biotec Laboratories near Omaha, Nebraska. At the facility, human leukocyte interferon production was carried out using recombinant DNA fermentation techniques in facilities separate from other work at the company. Six employees were assigned to the recombinant DNA project; 45 employees worked at the facility. An Institutional Bio-Safety Committee was formed in compliance with National Institutes of Health (NIH) guidelines. Work practices and emergency and accident procedures were reviewed. The authors conclude that Burns-Biotec Laboratories are meeting various relevant safety issues in a responsible manner. Specific recommendations are offered concerning validation procedures, facility design, work practices, and a medical surveillance program.

• Research Organization: National Inst. for Occupational Safety and Health, Cincinnati, OH (USA). Div. of Surveillance, Hazard Evaluation and Field Studies
• OSTI ID: 6924620
• Report Number(s): PB-88-221601/XAB; IWS-131.17
• Country of Publication: United States
• Language: English

Related Subjects

550300* -- Cytology
550400 -- Genetics
552000 -- Public Health
59 BASIC BIOLOGICAL SCIENCES
99 GENERAL AND MISCELLANEOUS
BACTERIA
BIOCONVERSION
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
DNA
ESCHERICHIA COLI
EVALUATION
FEDERAL REGION VII
FERMENTATION
GROWTH FACTORS
HAZARDS
INTERFERON
LABORATORIES
LEUKOCYTES
LYMPHOKINES
MATERIALS
MICROORGANISMS
MITOGENS
NEBRASKA
NORTH AMERICA
NUCLEIC ACIDS
OCCUPATIONAL SAFETY
ORGANIC COMPOUNDS
PRODUCTION
PROTEINS
RECOMBINANT DNA
SAFETY
USA