Use of computed tomography in diagnosing the cause of primary aldosteronism
Journal Article
·
· New Engl. J. Med.; (United States)
Computed tomography (CT) was performed in 22 consecutive patients with primary aldosteronism to evaluate the usefulness of this technique in diagnosing and locating aldosterone-producing adenomas. Sixteen patients had severe hypokalemia, hyperaldosteronism, and elevated plasma levels of 18-hydroxycorticosterone suggestive of an adenoma. In 12 of these 16, a unilateral adrenal mass was demonstrated clearly, and in all 11 who had surgery an adenoma was confirmed. In the other four patients in this group, one adrenal gland was normal and the other was either not seen adequately or had minor abnormalities that could not be definitely classified; and adenoma was found in the poorly visualized gland in each of the two patients who had surgery. The remaining six patients, who had milder biochemical abnormalities suggestive of idiopathic hyperaldosteronism, had bilateral adrenal enlargement or normal-appearing glands on scan and were not surgically explored.
- Research Organization:
- Univ. of California, San Francisco
- OSTI ID:
- 6921311
- Journal Information:
- New Engl. J. Med.; (United States), Journal Name: New Engl. J. Med.; (United States) Vol. 303:26; ISSN NEJMA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
550900 -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
ADRENAL GLANDS
ADRENAL HORMONES
ALDEHYDES
ALDOSTERONE
BODY
CAT SCANNING
COMPUTERIZED TOMOGRAPHY
CORTICOSTEROIDS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
GLANDS
HORMONES
HYDROXY COMPOUNDS
IMAGE PROCESSING
KETONES
MEDICINE
MINERALOCORTICOIDS
NEOPLASMS
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PLASMA
PREGNANES
PROCESSING
STEROID HORMONES
STEROIDS
SURGERY
TOMOGRAPHY
550900 -- Pathology
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
ADRENAL GLANDS
ADRENAL HORMONES
ALDEHYDES
ALDOSTERONE
BODY
CAT SCANNING
COMPUTERIZED TOMOGRAPHY
CORTICOSTEROIDS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
GLANDS
HORMONES
HYDROXY COMPOUNDS
IMAGE PROCESSING
KETONES
MEDICINE
MINERALOCORTICOIDS
NEOPLASMS
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PLASMA
PREGNANES
PROCESSING
STEROID HORMONES
STEROIDS
SURGERY
TOMOGRAPHY