INEL BNCT Research Program, March/April 1992

Technical Report · Tue Sep 01 00:00:00 EDT 1992

DOI:https://doi.org/10.2172/6913582· OSTI ID:6913582

Venhuizen, J R

This report presents summaries for two months of current research for the Idaho National Engineering Laboratory (INEL) Boron Neutron Capture Therapy (BNCT) Program. Information is presented on development and murino screening experiments of low-density lipoprotein, carboranyl alanine, and liposome boron containing compounds. Pituitary tumor call culture studies are described. Drug stability, pharmacology and toxicity evaluation of borocaptate sodium (BSH) and boronopheoylalanine (BPA) are described. Treatment protocol development via the large animal (canine) model studies and physiological response evaluation in rats are discussed. Supporting technology development and technical support activities for boron drug biochemistry and purity, analytical and measurement dosimetry, and noninvasive boron quantification activities are included for the current time period. Current publications for the two months are listed.

• Research Organization: EG and G Idaho, Inc., Idaho Falls, ID (United States)
• Sponsoring Organization: USDOE; USDOE, Washington, DC (United States)
• DOE Contract Number: AC07-76ID01570
• OSTI ID: 6913582
• Report Number(s): EGG-BNCT-10016-03/04; ON: DE93001931
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
NEUTRON CAPTURE THERAPY
RBE
RADIOPHARMACEUTICALS
ALBUMINS
BORON COMPOUNDS
BRAIN
LIPOSOMES
NEOPLASMS
PHENYLALANINE
PROGRESS REPORT
STH
AMINO ACIDS
BODY
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
DISEASES
DOCUMENT TYPES
DRUGS
HORMONES
LABELLED COMPOUNDS
MEDICINE
NERVOUS SYSTEM
NEUTRON THERAPY
NUCLEAR MEDICINE
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PEPTIDE HORMONES
PITUITARY HORMONES
PROTEINS
RADIOLOGY
RADIOTHERAPY
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)