Relationship between dietary copper intake and indices of copper status in men, premenopausal and postmenopausal women

Journal Article · Wed Feb 08 23:00:00 EST 1989 · FASEB Journal (Federation of American Societies for Experimental Biology); (USA)

OSTI ID:6896736

Panda, P; Reiser, S; Canary, J ^[1]

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1. Univ. of Maryland, College Park (USA)

Dietary copper (Cu) intake, red blood cell superoxide dismutase (SOD), ceruloplasmin (Cp) and plasma Cu were determined in 18 men, 18 premenopausal (PRE) and 18 postmenopausal (POST) women. Follicle stimulating hormone and leutinizing hormone were measured to verify menopausal status in women. SOD levels were significantly different in men, PRE and POST women and were used to divide subjects into adequate (350-700 U/mI) and inadequate (<350 U/ml) Cu status. Dietary Cu intake including supplements was highest for men (2.53 mg/day) as compared to PRE (1.35 mg/day) and POST (1.86 mg/day) women. There was an inverse correlation between dietary Cu intake and SOD levels. Plasma Cu levels were significantly higher in women (102.8 {mu}g/dl PRE, 108.95 POST {mu}g/dl) compared to men (88.34 {mu}g/dl). Cp levels showed a positive correlation with plasma Cu but did not show a sex effect. The present Cu intake levels were calculated from diet records using a food Cu data base. These results are in the process of being verified by direct analysis of Cu level in a 3 day food composite. The results indicate that Cu intake alone is not a good predictor of Cu status as determine by SOD levels.

• OSTI ID: 6896736
• Journal Information: FASEB Journal (Federation of American Societies for Experimental Biology); (USA), Journal Name: FASEB Journal (Federation of American Societies for Experimental Biology); (USA) Vol. 3:3; ISSN FAJOE; ISSN 0892-6638
• Country of Publication: United States
• Language: English

Related Subjects

550500* -- Metabolism
59 BASIC BIOLOGICAL SCIENCES
AGE GROUPS
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BLOOD PLASMA
BODY FLUIDS
CERULOPLASMIN
COMPLEXES
COPPER
COPPER COMPLEXES
DIET
ELEMENTS
ENZYME ACTIVITY
ENZYMES
ERYTHROCYTES
FEMALES
GLOBULINS
GLOBULINS-ALPHA
MALES
MAMMALS
MAN
MATERIALS
MEN
METABOLISM
METALLOPROTEINS
METALS
NUTRITION
NUTRITIONAL DEFICIENCY
ORGANIC COMPOUNDS
OXIDOREDUCTASES
PRIMATES
PROTEINS
SUPEROXIDE DISMUTASE
TRANSITION ELEMENT COMPLEXES
TRANSITION ELEMENTS
VERTEBRATES
WOMEN