Organic-soluble lanthanide nuclear magnetic resonance shift reagents for sulfonium and isothiouronium salts. [Eu(fod)/sub 3/; fod = 6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedione]

Journal Article · Sat Feb 14 23:00:00 EST 1987 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00131a006· OSTI ID:6881600

Wenzel, T J; Zaia, J

Lanthanide complexes of the formula (Ln(fod)/sub 4/)/sup -/ (FOD, 6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedione) are effective organic-soluble nuclear magnetic resonance shift reagents for sulfonium and isothiouronium salts. The shift reagent is formed in solution from Ln(fod)/sub 3/ and Ag(fod) or K(fod). The selection of Ag(fod) or K(fod) in forming the shift reagent is dependent on the anion of the organic salt. Ag(fod) is more effective with halide salts, whereas K(fod) is preferred with tetrafluoroborate salts. Resolution of diastereotopic hydrogen atoms was observed in the shifted spectra of certain substrates. Enantiomeric resolution was obtained in the spectrum of sec-butylisothiouronium chloride with a chiral shift reagent. The reagents can be employed in solvents such as chloroform and benzene.

• Research Organization: Bates College, Lewiston, ME
• OSTI ID: 6881600
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 59:4; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102* -- Chemical & Spectral Procedures
CARBONIC ACID DERIVATIVES
CHEMICAL ANALYSIS
COMPLEXES
EUROPIUM COMPLEXES
MAGNETIC RESONANCE
NUCLEAR MAGNETIC RESONANCE
ORGANIC COMPOUNDS
ORGANIC FLUORINE COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC SULFUR COMPOUNDS
QUANTITATIVE CHEMICAL ANALYSIS
RARE EARTH COMPLEXES
RESONANCE
SILVER COMPLEXES
SPECTRAL SHIFT
THIOUREAS
TRANSITION ELEMENT COMPLEXES