Bone and liver images in medullary carcinoma of the thyroid gland: concise communication

Journal Article · Sun Apr 01 04:00:00 EST 1984 · J. Nucl. Med.; (United States)

OSTI ID:6879933

Johnson, D G; Coleman, R E; McCook, T A; Dale, J K; Wells, S A

Thirty-four patients with surgically documented medullary carcinoma of the thyroid (MCT) and elevated serum calcitonin levels had Tc-99m phosphate bone and/or Tc-99m sulfur colloid liver images for suspected metastases. Liver images demonstrated metastatic lesions in nine of 32 patients (28%). Bone images were positive for metastases in eight of 30 patients (27%). Four of these eight abnormal bone studies detected only skeletal lesions, two demonstrated only extraosseous metastases, and two showed both kinds. This study demonstrates that radionuclide bone and liver images frequently detect metastatic lesions in patients with MCT and elevated serum calcitonin levels, and that some nonskeletal metastases in patients with this tumor display an unusual affinity for bone-seeking radiotracers.

• Research Organization: Duke Univ. Medical Center, Durham, NC
• OSTI ID: 6879933
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:4; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
550901 -- Pathology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARCINOMAS
COLLOIDS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
DISPERSIONS
ENDOCRINE GLANDS
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIVER
METASTASES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PATIENTS
PHOSPHATES
PHOSPHORUS COMPOUNDS
RADIOCOLLOIDS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
SKELETON
SULFUR COMPOUNDS
TECHNETIUM 99
TECHNETIUM COMPOUNDS
TECHNETIUM ISOTOPES
TECHNETIUM PHOSPHATES
THYROID
TRANSITION ELEMENT COMPOUNDS
YEARS LIVING RADIOISOTOPES