Changes in the blood count of growing rats irradiated with a microwave pulse field

Journal Article · Mon Jan 01 04:00:00 EST 1979 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1979.10667366· OSTI ID:6879593

Pazderov'a-Vejlupkov'a, J; Jos'ifko, M

A group of 20 male rats of mean initial body weight of 65.53 g were irradiated for 7 weeks (5 d per week, 4 h per d) with an electromagnetic pulse field of the following parameters: working frequency 2736.5 MHz; repeated frequency 395 Hz; pulse width 2.6 musec; vertical polarization; mean power density 24.4 mW/cm2; accuracy of measuring +- 6%. The rectal temperature of experimental animals increased during irradiation by a maximum of 0.5/sup 0/C. Blood was taken before irradiation, and at the end of the 1st, 3rd, 5th, and 7th weeks of irradiation, and at the end of the 1st, 2nd, 6th, and 10th weeks after irradiation was completed. The parameters under study included the hematocrit value; number of leukocyte differential count in both absolute and relative proportions; activity of alkaline phosphatase in neutrophil leukocytes; and body weight increase. The results were compared with a control group of 20 animals and evaluated at a significance level of 1%. In the second half of the irradiation period the experimental animals exhibited significantly lower mean hematocrit values, lower numbers of leukocytes, and lower absolute numbers of lymphocytes. These changes disappeared gradually within 10 weeks after completed irradiation. Activity of alkaline phosphatase in neutrophil leukocytes was significantly increased in the 1st week of irradiation and dropped transiently after the irradiation. In the post-irradiation interval experimental animals displayed significant decline in rate of body weight increase. The level of the other examined parameters did not differ from the controls.

• Research Organization: Charles Univ., Prague, Czechoslovakia
• OSTI ID: 6879593
• Journal Information: Arch. Environ. Health; (United States), Journal Name: Arch. Environ. Health; (United States) Vol. 34:1; ISSN AEHLA
• Country of Publication: United States
• Language: English

Related Subjects

551000 -- Physiological Systems
560400* -- Other Environmental Pollutant Effects
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALINE PHOSPHATASE
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BLOOD COUNT
BODY FLUIDS
CONNECTIVE TISSUE CELLS
ELECTROMAGNETIC RADIATION
ENZYMES
ESTERASES
HYDROLASES
LEUKOCYTES
LYMPHOCYTES
MALES
MAMMALS
MATERIALS
MICROWAVE RADIATION
NEUTROPHILS
PHOSPHATASES
RADIATION EFFECTS
RADIATIONS
RATS
RODENTS
SOMATIC CELLS
VERTEBRATES
WEIGHT