Mucociliary transport and particle clearance in the human tracheobronchial tree

Technical Report · Thu Jan 01 04:00:00 EST 1981

OSTI ID:6878448

Yu, C P; Hu, J P; Leikauf, G; Spektor, D; Lippmann, M

A compartmental model to describe mucociliary transport and particle clearance in the tracheobronchial trees was described. A method was proposed for determining the mucociliary transport rate as a function of the airway depth from the retention curve directly. Each airway generation was represented by an escalator. For Weibel's lung model there were 17 airway generations in the tracheobronchial tree. The subject performed a series of respiratory mechanical function tests prior to exposure to a monodisperse ferric-oxide aerosol tagged with technetium-99. The model was simple and appeared to describe the physical process well.

• Research Organization: State Univ. of New York, Buffalo (USA). Faculty of Engineering and Applied Sciences
• OSTI ID: 6878448
• Report Number(s): PB-88-247846/XAB
• Country of Publication: United States
• Language: English

Related Subjects

551001* -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
AEROSOLS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL PATHWAYS
COLLOIDS
DISPERSIONS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
MATHEMATICAL MODELS
METABOLISM
NUCLEI
ODD-EVEN NUCLEI
PARTICLES
RADIOISOTOPES
RESPIRATORY SYSTEM
SOLS
TECHNETIUM 99
TECHNETIUM ISOTOPES
TRACER TECHNIQUES
YEARS LIVING RADIOISOTOPES