Some effects of methylmercury on development of the eye in Medaka fish

Journal Article · Fri Sep 01 04:00:00 EDT 1978 · Growth; (United States)

OSTI ID:6859724

Dial, N A

Japanese Medaka (Oryzias latipes) eggs were treated with 80 parts per billion methylmercuric chloride for up to ten days. Developing eggs were removed at selected times and prepared for observation at the light and electron microscope levels. Treated embryos which were severely affected by methylmercury had poorly developed eyes with disorganized retina, abnormal pigment distribution, thick corneas and invasive blood sinuses in retinal tissue. There was also evidence of mitotic arrest. Embryos which appeared only slightly affected by methylmercury developed eyes which were similar to controls except for localized lesions and occasional small blood sinuses in the retina and less pigment in the pigmented epithelium. Electron microscopic observations revealed that subcellular structures were little affected in embryos little affected by methylmercury. Certain cells, however, showed intracellular lesions (cytoplasmic degradation).

• Research Organization: Indiana State Univ., Terre Haute
• OSTI ID: 6859724
• Journal Information: Growth; (United States), Journal Name: Growth; (United States) Vol. 42:3; ISSN GROWA
• Country of Publication: United States
• Language: English

Related Subjects

520200* -- Environment
Aquatic-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
ANIMALS
AQUATIC ORGANISMS
BIOLOGICAL EFFECTS
BIOLOGY
BODY
CELL DIVISION
CYTOLOGY
EGGS
ELECTRON MICROSCOPY
EMBRYOS
EYES
FISHES
METHYLMERCURY
MICROSCOPY
MITOSIS
ONTOGENESIS
ORGANIC COMPOUNDS
ORGANIC MERCURY COMPOUNDS
ORGANS
POLLUTION
SENSE ORGANS
VERTEBRATES
WATER POLLUTION