Sipple's syndrome with liver tumors examined by iodine-131 MIBG and technetium-99m(V)-DMSA

Journal Article · Wed Jun 01 04:00:00 EDT 1988 · J. Nucl. Med.; (United States)

OSTI ID:6859050

Ohta, H; Endo, K; Fujita, T; Koizumi, M; Konishi, J; Maki, A; Mori, K; Ozawa, K; Inoue, G; Nakano, Y

This case report describes the localization and categorization of tumors using /sup 99m/Tc(V)-dimercaptosuccinic acid and (/sup 131/I)metaiodobenzylguanidine scans in a very uncommon case of medullary thyroid carcinoma associated with pheochromocytoma (Sipple's syndrome) and hepatocellular carcinoma. Technetium-99m(V)-dimercaptosuccinic acid showed accumulation only in medullary thyroid carcinoma, but (/sup 131/I)metaiodobenzylguanidine scans were positive in both medullary thyroid carcinoma and pheochromocytoma. In advanced Sipple's syndrome, combined use of (/sup 99m/Tc(V))dimercaptosuccinic acid and (/sup 131/I)metaiodobenzylguanidine may be useful for the categorization of tumor mass lesions and planning appropriate therapy.

• Research Organization: Kyoto Univ. School of Medicine (Japan)
• OSTI ID: 6859050
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 29:6; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARCINOMAS
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIGESTIVE SYSTEM
DISEASES
DRUGS
ENDOCRINE GLANDS
GLANDS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 131
IODINE ISOTOPES
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIVER
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOPHARMACEUTICALS
TECHNETIUM 99
TECHNETIUM ISOTOPES
THYROID
YEARS LIVING RADIOISOTOPES