Quantitative analysis of normal thallium-201 tomographic studies
To determine the normal (nl) distribution of Tl-201 uptake post exercise (EX) and at redistribution (RD) and nl washout, Tl-201 rotational tomographic (tomo) studies were performed in 40 subjects: 16 angiographic (angio) nls and 24 nl volunteers (12 from Emory and 12 from Yale). Oblique angle short axis slices were subjected to maximal count circumferential profile analysis. Data were displayed as a ''bullseye'' functional map with the apex at the center and base at the periphery. The bullseye was not uniform in all regions because of the variable effects of attenuation and resolution at different view angles. In all studies, the septum: lateral wall ratio was < 1.0, as was the apex: lateral wall ratio. The anterior: inferior ratio was dependent, in part, upon gender and was > 1.0 in males and approximately equal to 1.0 in females. This occurred predominantly because of anterior defects due to breast soft tissue attenuation. EX and RD bullseyes were similar. Using a bi-exponential model for Tl kinetics, 4 hour normalized washout ranged 49-54% in each group and showed minimal variation between walls throughout the bullseye. Thus, there are well defined variations in Tl-201 uptake in the nl myocardium which must be taken into consideration when analyzing pt data. Because of these defects and the lack of adequate methods for attenuation correction, quantitative analysis of Tl-201 studies must include direct comparison with gender-matched nl data sets.
- Research Organization:
- Emory Univ., Atlanta, GA
- OSTI ID:
- 6855358
- Report Number(s):
- CONF-850611-; TRN: 87-010722
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
Similar Records
Quantitative rotational thallium-201 tomography for identifying and localizing coronary artery disease
Isolated scintigraphic abnormality of diffuse slow washout of myocardial thallium-201: Clinical and prognostic implications
Related Subjects
CAT SCANNING
IMAGE PROCESSING
HEART
SCINTISCANNING
MYOCARDIUM
BIOMEDICAL RADIOGRAPHY
BLOOD VESSELS
CHEST
DATA ANALYSIS
EXERCISE
METABOLISM
OPTIMIZATION
SEQUENTIAL SCANNING
THALLIUM 201
TISSUE DISTRIBUTION
UPTAKE
BETA DECAY RADIOISOTOPES
BODY
BODY AREAS
CARDIOVASCULAR SYSTEM
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISTRIBUTION
ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MEDICINE
MUSCLES
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PROCESSING
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
SECONDS LIVING RADIOISOTOPES
THALLIUM ISOTOPES
TOMOGRAPHY
550601* - Medicine- Unsealed Radionuclides in Diagnostics