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Obliteration of the mastoid in the treatment of tumors of the temporal bone

Journal Article · · Ann. Otol., Rhinol., Laryngol.; (United States)
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A retrospective analysis of 29 cases of squamous cell carcinoma of the external and middle ear and 15 cases of glomus jugulare tumors of the middle ear was performed to evaluate the incidence of osteoradionecrosis of the temporal bone following surgery and/or radiotherapy. Osteoradionecrosis occurred in 42% (8/19) of cases of squamous cell carcinoma which were treated with radical mastoidectomy, lateral or subtotal temporal bone resection leaving an open cavity and followed by an average of 5,840 rad postoperatively. No osteoradionecrosis, wound breakdown or otorrhea occurred in another group of six patients who were treated by surgical exenteration, total cavity obliteration, and an average of 5,700 rad of postoperative radiotherapy. Thus, cavity obliteration significantly decreased the incidence of these complications (p less than 0.05). In contrast, in 15 patients treated by surgery and postoperative irradiation (average dose . 4,610 rad) for glomus jugulare tumors, no osteoradionecrosis occurred despite use of an open cavity technique.

Research Organization:
Department of Otolaryngology, Harvard Medical School, Boston, MA
OSTI ID:
6847752
Journal Information:
Ann. Otol., Rhinol., Laryngol.; (United States), Journal Name: Ann. Otol., Rhinol., Laryngol.; (United States) Vol. 93:1; ISSN AORHA
Country of Publication:
United States
Language:
English

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Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AUDITORY ORGANS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DELAYED RADIATION EFFECTS
DISEASES
INJURIES
LOCAL RADIATION EFFECTS
MEDICINE
NECROSIS
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
OSTEORADIONECROSIS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
SENSE ORGANS
SIDE EFFECTS
SKELETAL DISEASES
SKELETON
SKULL
THERAPY