Patient-specific dosimetry based on quantitative SPECT imaging and 3D-DFT convolution
Conference
·
OSTI ID:684482
- Univ. of Nebraska Medical Center, Omaha, NE (United States)
The objective of this study was to validate the use of a 3-D discrete Fourier Transform (3D-DFT) convolution method to carry out the dosimetry for I-131 for soft tissues in radioimmunotherapy procedures. To validate this convolution method, mathematical and physical phantoms were used as a basis of comparison with Monte Carlo transport (MCT) calculations which were carried out using the EGS4 system code. The mathematical phantom consisted of a sphere containing uniform and nonuniform activity distributions. The physical phantom consisted of a cylinder containing uniform and nonuniform activity distributions. Quantitative SPECT reconstruction was carried out using the Circular Harmonic Transform (CHT) algorithm.
- Research Organization:
- Oak Ridge Associated Universities, TN (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG02-91ER61195
- OSTI ID:
- 684482
- Report Number(s):
- ORISE--99-0164-Vol.1; CONF-960536--PROC.-Vol.1; ON: DE99002903
- Country of Publication:
- United States
- Language:
- English
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