Mutagenicity of anthraquinone and hydroxylated antrhaquinones in the Ames/Salmonella microsome system
Journal Article
·
· Appl. Environ. Microbiol.; (United States)
OSTI ID:6841526
- Massachusetts Inst. of Tech., Cambridge
The mutagenicity of anthracene, anthraquinone, and four structurally similar compounds of each was evaluated in the Ames/Salmonella microsome assay.Anthraquinone was shown to be mutagenic for strains TA1537, TA1538, and TA98 in the absence of rat liver homogenate. The four anthraqunione derivatives tested were mutagenic for TA1537 exclusively. None of the anthracenes exhibited mutagenic activity.
- OSTI ID:
- 6841526
- Journal Information:
- Appl. Environ. Microbiol.; (United States), Journal Name: Appl. Environ. Microbiol.; (United States) Vol. 43:6; ISSN AEMID
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560302* -- Chemicals Metabolism & Toxicology-- Microorganisms-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANTHRACENE
ANTHRAQUINONES
AROMATICS
BACTERIA
BIOASSAY
CONDENSED AROMATICS
HYDROCARBONS
MICROORGANISMS
MUTAGEN SCREENING
MUTAGENESIS
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
QUINONES
SALMONELLA
SCREENING
STRUCTURAL CHEMICAL ANALYSIS
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANTHRACENE
ANTHRAQUINONES
AROMATICS
BACTERIA
BIOASSAY
CONDENSED AROMATICS
HYDROCARBONS
MICROORGANISMS
MUTAGEN SCREENING
MUTAGENESIS
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
QUINONES
SALMONELLA
SCREENING
STRUCTURAL CHEMICAL ANALYSIS