Reversible hydronephrosis in the rat: a new surgical technique assessed by radioisotopic measurements

Journal Article · Sun Apr 01 00:00:00 EST 1984 · J. Urol.; (United States)

OSTI ID:6834321

Flam, T; Venot, A; Bariety, J

A new technique for experimental reversible hydronephrosis in the rat was developed. A noninvasive radioisotopic investigation, using Tc-99m dimercaptosuccinic acid, permitted sequential assessment of the separate renal function at different stages of the study. After 1 week of unilateral ureteral obstruction, reversibility was obtained by the removal of the obstructive device. Ten days after the obstruction release, the ipsilateral kidney had returned to 71 per cent of its preligation uptake value. Histological findings demonstrated the reversibility of the surgical obstruction.

• Research Organization: Department of Urology, Hopital Cochin, Paris, France
• OSTI ID: 6834321
• Journal Information: J. Urol.; (United States), Vol. 131:4
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
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